Abstract: Aircraft are instruments flying in the atmosphere or outer space, including aircraft, spacecraft, rockets and missiles. During the maneuver of aircraft, the sectional loads (tension, compression, bending and torsion) of aircraft structure are important basis for structural design. The accuracy of load measurement results directly affects the reliability of structural design.Aiming at the difficulty of testing the internal stress of missile structure during flight, a method combining the measured strain load of load tester and LS_DYNA software for simulation analysis was proposed. Firstly, the stress performance of a single stringer component is verified by finite element simulation to confirm the measurement point layout of each stringer component. The load tester is designed for high-precision load measurement. The tester is composed of 8-channel strain measurement module and 6-channel temperature measurement module, and the system is jointly controlled by MCU and FPGA. The linearity of the signal is improved through strain signal conditioning circuit and temperature signal conditioning circuit, and a large amount of data is stored by Flash. Upload data to the last computer via RS422 to USB. Load tester for high precision acquisition scheme is verified by the above work, the results show that the load tester to the data of strain and temperature data has high linearity, were superior to the existing load test device, for the projectile structure design of missile has the certain reference value.